Cellular adaptation to opiates alters ion-channel mRNA levels.
نویسندگان
چکیده
منابع مشابه
15. Ions, Opiates and Cellular Adaptation
The pharmacological actions of opiate drugs are best characterized by sedation, analgesia, respiratory depression and changes in temperature. Repeated exposure to opiates, however, produces tolerance to these effects such that the magnitude of response is much reduced or absent. From this it must be assumed that the binding of opiates to their receptor sites activate certain biochemical events ...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1994
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.91.1.385